专家文章 | 郭颖杰

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热心肠智库专家文章 | 郭颖杰

2023

CAProbiotics attenuate valproate-induced liver steatosis and oxidative stress in mice

PLoS 1, 10.1371/journal.pone.0294363

CADecreased plasma exposure of clopidogrel active metabolite in rats after long-term treatment with clopidogrel

BIOPHARM DRUG DISPOS, 10.1002/bdd.2349

2022

CAAntibiotics-induced disruption of gut microbiota increases systemic exposure of clopidogrel active metabolite in type 2 diabetic rats

DRUG METAB DISPOS, 10.1124/dmd.122.000906

2020

CAInvolvement of CYP2E1-ROS-CD36/DGAT2 axis in the pathogenesis of VPA-induced hepatic steatosis in vivo and in vitro

TOXICOLOGY, 10.1016/j.tox.2020.152585

CAType 2 diabetes mellitus decreases systemic exposure of clopidogrel active metabolite through upregulation of P-glycoprotein in rats

Biochem. Pharm, 10.1016/j.bcp.2020.114142

2019

CAEnhanced Platelet Response to Clopidogrel in Zucker Diabetic Fatty Rats due to Impaired Clopidogrel Inactivation by Carboxylesterase 1 and Increased Exposure to Active Metabolite

DRUG METAB DISPOS, 10.1124/dmd.118.085126