专家文章 | 郝海平

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热心肠智库专家文章 | 郝海平

2024

CAGinsenosides retard atherogenesis via remodelling host-microbiome metabolic homeostasis

BR J PHARMACOL, 10.1111/bph.16320

CADiscovery of proqodine A derivatives with antitumor activity targeting NAD(P)H: quinone oxidoreductase 1 and nicotinamide phosphoribosyltransferase

Chin J Nat Med, 10.1016/S1875-5364(24)60564-9

CAPsychological stress-induced microbial metabolite indole-3-acetate disrupts intestinal cell lineage commitment

Cell Metab, 10.1016/j.cmet.2023.12.026

CAA Gpr35-tuned gut microbe-brain metabolic axis regulates depressive-like behavior

Cell Host Microbe, 10.1016/j.chom.2023.12.009

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2023

CAExhaustively Exploring the Prevalent Interaction Pathways of Ligands Targeting the Ligand-Binding Pocket of Farnesoid X Receptor via Combined Enhanced Sampling

J CHEM INF MODEL, 10.1021/acs.jcim.3c01451

CAFXR agonists for MASH therapy: Lessons and perspectives from obeticholic acid

MED RES REV, 10.1002/med.21991

CASTING signaling in islet macrophages impairs insulin secretion in obesity

Sci China Life Sci, 10.1007/s11427-022-2371-9

CAGinkgo biloba extract protects against depression-like behavior in mice through regulating gut microbial bile acid metabolism

Chin J Nat Med, 10.1016/S1875-5364(23)60496-0

CAIntracellular spatiotemporal metabolism in connection to target engagement

Adv Drug Deliv Rev, 10.1016/j.addr.2023.115024

CAChemoproteomic mapping of the glycolytic targetome in cancer cells

Nat Chem Biol, 10.1038/s41589-023-01355-w

CAPolyunsaturated fatty acids drive neutrophil extracellular trap formation in nonalcoholic steatohepatitis

EUR J PHARMACOL, 10.1016/j.ejphar.2023.175618

CABile acids target mitofusin 2 to differentially regulate innate immunity in physiological versus cholestatic conditions

Cell Rep, 10.1016/j.celrep.2023.112011

2022

CACooperation of structural motifs controls drug selectivity in cyclin-dependent kinases: an advanced theoretical analysis

BRIEF BIOINFORM, 10.1093/bib/bbac544

CADiscovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors

J MED CHEM, 10.1021/acs.jmedchem.2c01452

CAMetformin Hydrochloride Mucosal Nanoparticles-Based Enteric Capsule for Prolonged Intestinal Residence Time, Improved Bioavailability, and Hypoglycemic Effect

PharmSciTech, 10.1208/s12249-022-02402-w

CAComprehensive metabolomic profiling of nutrients in fish and shrimp

FOOD CHEM, 10.1016/j.foodchem.2022.135037

CALiving Cell-Target Responsive Accessibility Profiling Reveals Silibinin Targeting ACSL4 for Combating Ferroptosis

ANAL CHEM, 10.1021/acs.analchem.2c03515

CAAberrant branched-chain amino acid accumulation along the microbiota-gut-brain axis: Crucial targets affecting the occurrence and treatment of ischaemic stroke

BR J PHARMACOL, 10.1111/bph.15965

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CAAberrant BCAA Accumulation along the Microbiota-Gut-Brain Axis:Crucial Targets Affecting the Occurrence and Treatment of Ischemic Stroke

BR J PHARMACOL, 10.1111/bph.15965

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CADetermination of Molecule Category of Ligands Targeting the Ligand-Binding Pocket of Nuclear Receptors with Structural Elucidation and Machine Learning

J CHEM INF MODEL, 10.1021/acs.jcim.2c00851