Research synopsis:
The long-term interest of our laboratory is to bridge molecular, cellular, and system approaches to understand the neuronal modulation and circuitry involved in the pathogenesis of neurological diseases. Specifically, we are currently leveraging and combining a cornucopia of cutting-edge technologies, from genetically engineered mouse models, recombinant viral vectors and viral tracing system, optogenetic and pharmacogenetic approaches, patch-clamp electrophysiology, to 2-photon laser scanning microscopy and 2-photon laser uncaging methods (2PLSM/2PLU), to explore the molecular and circuit mechanisms underlying feeding related behaviors and metabolic homeostasis.
研究概要：
我们实验室的长期方向是将分子、细胞和系统方法联系起来，以了解神经疾病发病机制中涉及的神经调节和神经回路。 具体而言，我们结合使用多种尖端技术，从基因工程小鼠模型、重组病毒载体和病毒追踪系统、光遗传学和药物遗传学方法、膜片钳电生理学，到双光子激光扫描显微镜和双光子激光解笼方法（2PLSM / 2PLU），探讨进食相关行为和代谢稳态的分子和神经回路机制。
