近期,来自海南大学张家超团队与UCSD的Rob Knight合作在Microbiome上发表文章Candidate probiotic Lactiplantibacillus plantarum HNU082 rapidly and convergently evolves within human, mice, and zebrafish gut but differentially influences the resident microbiome,以植物乳杆菌HNU082(Lp082)为益生菌模型菌株,揭示其在不同宿主肠道中高度趋同的适应过程和策略。相反,宿主肠道菌群对Lp082的引入呈现出不同反应与互作。而作为‘暂驻菌’,益生菌的引入对肠道常驻菌群遗传组成的影响常常被忽略。